Rapidly Progressive Glomerulonephritis in Children: An Analysis of 18 cases.
Abstract
Summary: The clinical course as well as the renal pathology in 18 children with rapidly progressive glomerulonephritis is described. The disease was charac terised by prolonged oliguria, generalised oedema, hypertension, hypoalbuminaemia and anaemia. Fifty-four per cent of the patients tested had hepatitis-R surface antige naemia. Deposition of immunoglobulins and complement occurred in the glomeruli of all the six kidney biopsies tested. The prognosis was poor, with 39% mortality. There were two defaulters and nine patients are alive. Of the nine living patients, seven have developed features of chronic renal disease.
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