Pattern of Decline of Foetal Hacmoglobin in Healthy Full-term Infants.
Abstract
Summary: Foetal haemoglobin levels were serially determined, using the modified Betke alkaline denaturation method between the ages of 1 day and 6 months, in a cohort of 99 healthy full-term babies. The mean values (percent) were: 1 day 70.2+10.6, 1 week 63.8+10.1, 2 weeks 57.3+10.6,6 weeks 44.2 +12.3, 3 months-16.9+6.8, 6 months 3.4+3.5. This pattern of decline of foetal haemo. globin was identical with those reported from most parts of the world. Foetal birth weight and sex, maternal parity, method of delivery and the presence of haemoglobin S in the heterozygous form did not influence the values.
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