Observations on the Seasonal Pattern of Burkitt's Lymphoma in Ibadan
Abstract
Summary:The monthly, quarterly, and half-yearly distribu tion of cases of Burkitt's lymphoma in Ibadan, from January 1962 to December 1974, was determined and compared with the concommitant rainfall and tempera ture patterns. The distribution of the tumour during the two climatic seasons of each year (namely: dry and wet seasons) was also determined. Analysis of these data have revealed no significant monthly, quarterly, half-yearly or seasonal variation in the incidence of the tumour. It is postulated that endemic malaria and Epstein-Bart virus infections are not the sole determinants of Burkitt's lymphoma oncogenesis but that a milieu of immunosuppression due to malnutrition and intercurrent infections are also important in the pathogenesis of the tumour.
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