D-xylose Absorption in Children with Sickle-Cell Anaemia.
Abstract
Summary: Oral D-xylose absorption tests were carried out on 25 children with sicklc-cell anacmia (genotype S) and on 25 age-matched non-anaemic controls with genotype A. Timed blood D-xylose values and 5 hours urinary excretion values of D-xylose were significantly lower (P<0.001) in the chil dren with sickle-cell anaemia. It is concluded that intestinal absorption of D-xylose is considerably reduced among children of the test group and the possible pathophy siologic mechanisms are discussed.
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