Clinical Trial of Isoprinosine in Measles.
Abstract
Summary: A placebo-controlled double-blind clinical trial of isoprinosine was carried out in 100 children with acute measles. The criteria used for assessing patients' response to treatment were clinical course of the disease and the rate of fall in temperature. When clinical course was used as the criterion, 85% of the patients on isoprinosine and 70% of patients on placebo responded well to treatment; the difference is not statistically significant. The temperature response of patients treated with iso prinosine was not significantly different from the response of patients who received placebo. However, all the four deaths occurred in the placebo group.
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