Cord Blood Alphafoetoprotein Levels in Gestational Age Assessment.
Abstract
Summary: Alphafoetoprotein (AFP) was determined in the scra of 113 nomal infants of gestational age ranging from 27 to 43 weeks, using double antibody radio-immunoassay technique. Gestational age was determined, using the Dubowitz criteria. The mean AFP values, though within the range of normal values, were higher at all gestational ages than those reported for other races. The AFP values were not influenced signifi cantix by the scx or birthweight of the infant. There was a significant degree of negative correlation between AFP and gestational age, r=-0.77 (P = 0.001). The 95 percent confidence limit for estimating gestational age from a single reading of AFP was + 4.2 Weeks.
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