Prevalence of neonatal septicaemia in the University of Port Harcourt Teaching Hospital, Nigeria

Abstract

Abstract Background : Septicaemia is a major cause of morbidity and mortality in the neonatal period. Early detection  of neonatal septicaemia is often hampered by its subtle and nonspecific symptoms and signs thus a high index of suspicion is
needed.

Objectives: To determine the p r e v a l e n c e o f n e o n a t a l sept ic a emia , ident i fy the  predisposing factors, clinical features and causative organisms in the University of Port Harcourt Teaching Hospital.

Methods: Four hundred and six neonates with clinical suspicion of sepsis were recruited into the study over a six months period.
Blood culture was used as gold standard for the diagnosis of neonatal septicaemia.

Results: One hundred and sixtynine(41.6%) neonates had positive blood culture giving a prevalence rate of neonatal septicaemia as 33.1%. The predominant predisposing factors were out-born delivery (68.0%), birth asphyxia (30.2%) and prematurity (21.4%) while the major clinical features of septicaemia were respiratory distress (30.2%), fever (26.6%) and poor suck (22.5%). Klebsiella
pneumoniae ( 6 5 . 4 % ) , Staphylococcus aureus (15.4%) and Escherichia coli (7.7%) were the commonest organisms isolated in neonates with septicaemia.

Conclusion: Prevalence of blood culture-proven septicemia is high, being 33.1%. Klebsiella pneumoniae is the predominant cause of neonatal septicaemia in Port Harcourt.

Keywords: Neonatal septicaemia; Prevalence; Port Harcourt.