Glucose-6 Phosphate Dehydrogenase (G-6-PD) Status, Aflatoxins and Neotanal Jaundice

Abstract

Summary: In the present study of G-6 PD status, aflatoxins and neonatal jaundice, involving, 78 jaundiced and control in-born babies and 124 jaundiced and control out-born infants, G-6 PD was deficient in more male jaundiced babies (in-and out-borns) than in the controls (P<0.001). Aflatoxins were detected from cord blood in 30.0 percent of all the in-born babies and from peripheral blood in 24.2 percent of all the out-born infants. Relationship between G-6-PD activity in the 77 jaundiced and control in-born babies, prenatal exposure to aflatoxins and the presence of jaundice, revealed no correlation between cord blood concentra tion of aflatoxins and G-6-PD activity in either the jaundiced babies (P>0.05), or in the controls (P>0.05). The frequency of aflatoxin detection in peripheral blood in relation to G-6-PD status and the presence or absence of jaundice.