Aspergillus Meningitis in a Seven-year-old Girl with AIDS: a Case Report

Abstract

Abstract:  A seven-year-old girl presented with one-month history of fever and progressive weight loss, and a two-week history of multiple generalized tonic-clonic seizures with associated somnolence. She had vomited three times since the onset of seizures. She was initially managed at a church for what the parents thought was epilepsy but was eventually taken to two private hospitals where she received various drugs without any improvement. She presented in our hospital where a diagnosis of aspergillus meningitis was eventually made from cerebrospinal fluid analysis. Despite the commencement of fluconazole on the fourth day of admission, the patient died five days later. This case report focuses on the importance of this rare disease in immunocompromised children, as well as the diagnosis and limitations in management in a
resource poor setting.

Keywords: Aspergillus, meningitis, AIDS